Synthio Chemicals, LLC

Synthio Chemicals, LLC

Chemistry for a new millennium


Process intensification for chemical synthesis

Headquartered in in Boulder, Colorado, Synthio provides materials and design services to customers worldwide. Our firm specializes in the application of process intensification techniques to industrial-scale synthesis of fine chemicals. Whether you are seeking competitive advantages through new process development, working to stave off competition from China and India, or seeking to improve the safety of your hazardous production processes, Synthio's technology can make your business more competitive. We bring extensive experience and professionalism to every project and customize our support to your individual needs and concerns.

Our principals have decades of experience, in fields from energy storage to fuel cells and fluorinated pharmaceutical intermediates. We have built systems with production rates of tens of tons per year, integrated full process trains with alkylation, metathesis, separation, purification and drying into refrigerator-sized automated systems, and delivered tremendous value to our clients.

Get in touch with us to set up a consultation, or use the contact form at the bottom of this page to inquire whether our services are right for you.




4600 Nautilus Ct. South
Boulder, CO 80301

(720) 340-3715

Focus Areas

Process Intensification

Still doing chemistry like a 14th-century alchemist?  Batch processes, many steps, low yields and excess waste? Our 21st-century solutions enable us to access new process conditions not possible in conventional reactors. These processes cost less to implement and operate, scale more easily, produce product with superior quality, and pose fewer hazards than conventional batch reactors. 

Ionic liquids

Ionic liquids provide unique solutions as solvents in chemical processes and battery electrolytes. Synthio provides electrochemical-grade (<1000 ppm impurity) ionic liquids at the industrial scale. See our products page to order ionic liquids, lithium salts and formulated electrolytes with optimized additive packages. 

Fluorinating agents

Synthio's novel approach to fluorination will challenge all of your assumptions about this process. Compact, cost-effective, and above all safe, our processes can yield more than 100X the throughput of conventional batch fluorination.


On-site production

Process intensification can dramatically shrink the size of synthesis trains, enabling hazardous chemicals to be synthesized on-site, often from refrigerator-sized reactors. By eliminating the need to store hazardous or unstable chemicals, on-site production-on-demand can radically reduce both cost and risk.  

DiCarboxylic acids and derivatives

Dicarboxylic acids have unique properties that make them attractive building blocks for pharmaceuticals and cosmetics. Low toxicity, fast biodegradability and tunable hydrophilicity are among their unique properties. Synthio's continuous selective oxidation technology yields dicarboxylic acids like 3,6-dioxaoctanedioc acid (DOODA) at breakthrough cost/purity ratios. 

Highly energetic reactions

Our founders started their careers designing cooling systems for nuclear fusion reactors.  Fast, highly energetic reactions subject to runaway are our bread-and-butter. With novel heat exchanger/reactors fabricated in-house, our production systems can operate happily (and safely) well into regimes that would be explosive in convention equipment


Process intensification
is a strategy for making dramatic reductions
in the size of a chemical plant so as to
reach a given production objective
— C. Ramshaw


Let's Chat.

Use the form below to contact us regarding your process or chemistry challenge. Please be as detailed as possible. Include your industry along with any specific document requests. To help us best service your inquiry, we recommend that you first describe the issue you’re having before telling us what you want to achieve. You may also email or call us to make an appointment.

For job opportunities, please email us your resume. We’re always looking for new and exceptional talent to lead the firm into uncharted fields of chemical and process engineering.

Name *
Please do not include confidential or sensitive information in your message. If confidential information is required to understand your problem, we can execute an NDA prior to confidential discussions.